Tip 1: Esperal: dosage methods and indications for use
Tip 1: Esperal: dosage methods and indications for use
"Esperal" is a medical product,which is used in the treatment of alcoholism. After taking the medicine, the patient has unpleasant sensations that discourage the desire to consume alcohol. Depending on the degree of development of alcoholism, the drug can be administered at various dosages.
Indications for useEsperal is used for preventionmanifestations of alcoholism. The medicine can be used as an integral part of therapy in the treatment of alcohol dependence. Also, the drug is used for chronic poisoning with nickel, which is also most often the result of excessive consumption of alcoholic beverages. The drug has no other purpose. Esperal is not recommended if the patient has an increased sensitivity to disulfiram (the main active substance). It is forbidden to prescribe the drug for serious violations of liver function. The drug is contraindicated in diabetes, neuropsychological disorders, ischemia, epilepsy. Tablets are not prescribed within 24 hours after the last intake of an alcoholic beverage. It is not recommended to use the drug during breastfeeding and during pregnancy. "Esperal" is available in the form of tablets, which can be prescribed only by the doctor in charge because of the large number of side effects. Among the possible negative effects of the drug there is a metallic taste in the mouth, and in very rare cases, hepatitis, headaches, skin allergic reactions, memory deterioration can be seen.
Reception of the drugBefore taking the drug,preliminary assessment of the patient's health, a thorough examination is appointed. With the patient, a conversation is held about the possible consequences of taking the medicine. The doctor should warn a person about possible complications during the treatment and about the regimen of taking tablets. Usually the drug is prescribed in a dosage of 500 mg once a day during the morning meal. Dosage may be reduced by the attending physician. In addition to alcohol therapy, a diet can be prescribed. The dosage can also be increased depending on the patient's response if the prescribed amount of the drug does not have the desired effect. After 7-10 days the doctor spends an alcohol test and gives the patient no more than 30 ml of vodka (40% ethanol). If the reaction to a drunk dose of alcohol is weak, the total dosage should not exceed 120 ml. The sample is repeated in the hospital for 11-12 days of treatment. Then, additional tests may be required on an outpatient basis (2-3 days after the last test). On the basis of the reaction, the dosage of alcohol or drug is adjusted. In the future, the drug is used as part of maintenance therapy at a dosage of 150-200 mg. Further treatment is carried out for a period not exceeding 3 years.
Tip 2: "Esperal": reviews and instructions for use
"Esperal" is a drug for the treatment of alcoholism. Its use forms a persistent negative effect on alcohol. The active component of the drug is disulfiram.
"Esperal": indications, contra-indications, reviewsEsperal is available in the form of tablets fororal administration, tablets for subcutaneous implantation, gel. As a remedy for alcoholism, the drug is prescribed at that stage of dependence, when the patient is not able to control the amount of alcohol consumed. The drug is used to prevent relapse during treatment of alcohol dependence, as a detoxification agent for nickel poisoning during the treatment of chronic alcoholism. "Esperal" increases the concentration of ethyl alcohol metabolites with alcohol, resulting in nausea, vomiting, flushing of the face, general malaise, lowering of blood pressure. The reaction of the body to taking alcohol on the background of the drug can be quick and delayed. With a rapid reaction, there are violations from the cardiovascular and central nervous system. With delayed reaction, the patient can develop toxic hepatitis, damage to the kidneys, pancreas. The medication is contraindicated in cases of severe cardiovascular diseases (myocarditis, cardiovascular failure), hypersensitivity to components, neuropsychiatric diseases, renal or hepatic insufficiency, diabetes, epilepsy, during pregnancy, lactation. According to many reviews, after taking the drug there is a metallic taste in the mouth, allergic reactions, headaches, polyneuritis of the lower extremities, psychosis. There may be a decrease in memory, confusion, optic neuritis, gastritis. According to reviews, in rare cases, there are thrombosis of cerebral vessels, asthenia, hepatitis.
Do not use the product if the patient has taken alcohol or drugs containing ethyl alcohol within the previous 24 hours.
Instruction for the use of the drug EsperalBefore using Esperal, the patient does notshould drink alcoholic beverages within two to three days. In the form of tablets, the drug should be taken once a day (in the morning, at breakfast) in the amount of 0.5 g. 8-10 days after the start of the drug should be performed teturam-alcohol test. It is repeated in the hospital - after one or two days and outpatient - after three to five days. Further, "Esperal" is used in a maintenance dose of 0.150-0.2 g per day for one to three years.
In the form of a gel, "Esperal" is implanted and manifests its effect similarly to tablets.Implant tablets "Esperal" need to be enteredin the muscle tissue of the upper part of the buttocks or in the left iliac region to a depth of 4 cm. The drug is implanted after anesthesia and disinfection. The total dose of the medicament administered is eight tablets (0.8 g). At the end of the implantation, a seam and a sterile bandage are placed on the incision. The duration of the drug is determined by dosage and is selected individually in each case (from 6 months to 5 years).