Tip 1: What is sedation?

Tip 1: What is sedation?



Sedation is an effectSedative on the human body. These drugs are used to help people relax and not feel uncomfortable during certain medical procedures. The effect of soothing medication comes when the patient drinks it with water, inhales it, or receives a prick in a vein.





Sedation is caused by preparations based on certain plants, for example, valerian

















Why do you need a sedative effect?

There are two reasons for the use of sedativesMeans. First, they help painlessly survive certain surgical interventions and get rid of anxiety and fear. Secondly, they help to calm the least "obedient" patients, for example, children. They are also used in cases where the patient needs to maintain a stationary position for a long time. Often, sedatives are used together with painkillers.

Sedation and anesthesia

The sedative effect is mild and deep. Moderate sedation occurs as a result of the application of local anesthesia, that is, anesthesia of individual parts of the body. Often, local anesthesia is carried out in the treatment of teeth, plastic surgery. In this case, a person exposed to a sedative is able to maintain awareness, hear and understand speech, respond to touch. The patient is able to control all the vital functions of his body. Moderate sedation lasts not for long, but causes side effects: the patient may feel drowsy. Other side effects are nausea and headache. Sometimes there is a short-term memory loss. Patients who have undergone a mild sedative effect, doctors do not recommend signing important documents, driving a car, drinking alcohol and using the equipment within 24 hours after the procedure. Deep sedation occurs as a result of general anesthesia. At the same time, the reflex reactions of the organism, the ability to control breathing and answer questions are partially or completely lost.
After a deep sedative effect, the patient returns to normal longer, the risk of complications from anesthesia increases.

What drugs cause sedation?

Sedative medications are divided into tranquilizers,The purpose of which is to eliminate anxiety of patients, hypnotics and antipsychotics. Some tranquilizers in large doses act as hypnotic drugs, for example, benzodiazepine.
With increasing doses of sedative, the sedative effect is enhanced.
Among the drugs that causeSedative effect, secrete barbiturates, benzodiazepines, natural remedies, Z-drugs and antihistamines. Barbiturates include: amobarbital, pentobarbital, seconal, phenobarbital. Benzodiazepines include clonazepam, diazepam, estazolam, flunitrazepam, lorazepam, midazolam, nitrazepam, oxazepam, triazolam, temazepam, chlordiazepoxide, alprazolam. Natural sedatives include herbal remedies such as ashvagandha, duboisia, cats, kava-kava , Mandrake, valerian, marijuana. Z-drugs are zaleplon, zolpidem, zopiclone. Antigistamines include diphenhydramine, dimenhydrinate, doxylamine, phenergan, promethazine.
























Tip 2: What are sedatives, how they work



Sedatives are psychotropicDrugs that have a calming effect on the central nervous system (CNS) without significant disruption of its functions. Such drugs are used in medicine mainly for the treatment of neurotic conditions.





What is sedation, how do they work?







Sedatives and their types

Drugs of this group are able to lowerThe excitability of the central nervous system, to exert a regulatory influence on it, restoring the equilibrium between the processes of excitation and inhibition, and, if necessary, enhance the inhibition processes. Sedatives have a less pronounced psycho-sedative effect than tranquilizers, and do not possess hypnotic and miorelaxing properties, and, importantly, do not cause ataxia. With the systematic use of sedatives for a long time, mental drug dependence does not arise. In recommended therapeutic doses, sedatives can not have a hypnotic effect. But, providing a calming effect on the central nervous system, they can provoke the onset and deepening of sleep. Sedate preparations of synthetic and plant origin are distinguished. From herbal preparations, medicinal plants have been widely used, such as: heartwyrder, valerian officinalis, licorice balm, patronia medium (valerian stone), passionophilia incarnate, peony evading and tropical plants of the family of pepper cava-kava. Pharmacological effects of plant sedatives are very diverse. For example, valerian drug in addition to the sedative effect associated with a decrease in the excitability of the central nervous system, has antispasmodic properties, improves coronary circulation, regulates heart function, increases secretion of the glands of the gastrointestinal tract and improves bile secretion. Similar to valerian influences on the body is the motherwort, also having an antihypertensive effect and decreasing the heart rate. Passion flora and peony have an additional anticonvulsant effect. Melissa has antipruritic, antihypertensive, antispasmodic, and anti-arrhythmic action. In addition, it has a mild choleretic effect, favorably restores intestinal microflora and activates the secretion of the gastrointestinal tract. Kava-kava provides excellent sleeping pills, antimicrobial, and analgesic action.

Medicines with sedative effect

Soothing effect is also characteristic forSome drugs that are often not considered, as a means of influencing CNS. For such drugs, the sedative effect is concomitant with the underlying pharmacological effects. For example, a pronounced sedative effect is observed when using the diuretic acetazolamide ("Diacarb"), some antihypertensive agents - clonidine hydrochloride ("Clofelin"), or methyldophes. Some antihistamines, in particular diphenhydramine hydrochloride ("Dimedrol") and diprazine, have sedative and in some cases even a hypnotic effect. To achieve the best therapeutic effect, it is very important to choose the right drugs or the appropriate combination of drugs and determine the most effective dose that can be determined Only an expert after a preliminary consultation.